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Market Forces Demand Game-Changing Fertility Control

Wild and feral animals

STAGE 1: Wild Animals.

  • Feral horses in USA, Australia and Danube River Delta in Europe-- billions spent managing over population.
  • Feral burros are a global challenge with an estimated 10 million feral animals globally on six continents.
  • Deer overpopulation in urban areas cause billions of dollars in property damage, spread tick-borne diseases and billions of dollars in vehicle collisions. Hundreds of millions of dollars are spent annually on deer remediation.

Aquaculture and agricultural production animals

STAGE 2: Aquaculture and production animals In agriculture.

  • Farm-raised female fish put the majority of their energy into egg production spawn, so delaying or preventing sexual maturation will have direct economic benefit.
  • There are also environmental concerns about farm-raised fish that escape and breed with their wild counterparts, because they may produce offspring that are less suited to surviving in the wild.

Companion animals

STAGE 3: Companion Animals

  • The primary fertility control method used around the world for cats and dogs is surgery, which isn’t feasible in many regions. Research will first focus on fertility control applications for over a billion feral dogs and cats. Initial dosing, safety and efficacy results will then be applied to pivotal trials that demonstrate SpayVac’s efficacy as a fertility control vaccine for companion animals.”

Three-Stage Development Strategy for fertility-control vaccines: Fast, Efficient, Cost Effective

SpayVac for Wildlife Inc. is initiating its first Stage-2 development program in 2024.
Stage -1: SpayVac for Wildlife Inc. has completed Stage-1 fertility-control trials withSpayVac® (pZP vaccine) in horses, and deer.  We are  working through the process of filing for regulatory approval for these species.
Stage-2: Trials are scheduled to begin in farm-raised rainbow trout and farm-raised Atlantic salmon.
To learn more about the excellent clinical trial results with SpayVac pZP vaccines go to our R&D page.

THE SPAYVAC TECHNOLOGY ADVANTAGE

The Key is Antigen Presentation to Immune Cells

SpayVac is formulated in patented, leading-edge delivery platforms that are the cornerstone of our vaccine development pipeline. SpayVac has exclusive global rights for use in animals for fertility control. The platform is called VacciMax. It is a patented vaccine delivery formulation that provides controlled and prolonged exposure of antigens plus adjuvant to the immune system. The result is a strong, specific, and sustained immune response with the capability for single-dose effectiveness. It offers a robust and scalable engine for delivering many different targets that activate and direct immunocontraception in a controlled, impactful way.

Why this matters?

The proprietary advantage starts with a groundbreaking delivery formulation that is a powerful mechanism to present the pZP antigen in the case of SpayVac to the animal’s immune system, and sustain this presentation over a long timeframe. This platform utilizes a proprietary, extraordinarily stable “NO-RELEASE” delivery system utilizing highly engineered liposomes, which mitigates the propensity for antigens to break down, thereby extending the stimulation of the immune response.
SpayVac pZP vaccine is in the EPA approval process for horses and deer. Once approved we will be able to get future vaccines approved more quickly.

SPAYVAC

Creating humane fertility control vaccines for animals
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